6/12/2023 0 Comments فيلم by Mahdi Abdu![]() ![]() ![]() Results: Findings demonstrated that moderate endurance swimming exercise significantly prevented the increasing effect of nandrolone on HYP and MDA (P<0.01) but had no effect on GPX level of heart tissue. Thereafter a small piece of heart was frozen to measure Hydroxyproline (HYP) as an index of heart fibrosis, malondialdehyde (MDA) as an index of lipid peroxidation, and Glutathione peroxidase (GPX), an important antioxidant enzyme. At the end of period, animals were sacrificed, the hearts were removed and weighed and hypertrophy index was estimated as heart weight (mg)/body weight (g). ![]() ![]() Materials and Method: Animals were divided into 6 groups: control group, Exercise : 8 weeks under moderate endurance swimming training, vehicle group: received arachis oil as the solvent of nandrolone, nandrolone group: received nandrolone decanoate 5 mg/kg two times in week for 8 weeks. Due to some unknown about the interaction between misuses of anabolic-androgenic steroids and exercise on cardiovascular system, this study assessed the effect of chronic consumption of nandrolone decanoate along with moderate endurance swimming exercise on cardiac hypertrophy, hydroxyproline and redox system of heart tissue. ![]()
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